Budde E, Naumann G, Nimmich W, Schmicker R, Günther M, Töwe J
Infection. 1976;4(3):153-8. doi: 10.1007/BF01638942.
Using the direct immunofluorescence technique antibody-coated bacteria were demonstrated in urine samples from 49 of 57 patients with the clinical diagnosis of chronic pyelonephritis, but were not observed in urines from 11 patients with cystitis. A correlation rate was found between the presence of antibody-coated bacteria in the urine seidment and elevated serum antibody titers in the pyelonephritis group as determined by the indirect immunofluorescence technique. Patients with elevated serum antibody titers without antibody-coated bacteria in the urine, and vice versa, were also found. Patients with cystitis did not have elevated serum antibody titers against the homologous strain isolated from the urine. The clinical diagnosis of chronic pyelonephritis could be confirmed in 86.5% of patients taking into account the presence of antibody-coated bacteria and/or elevated serum antibody titers.
采用直接免疫荧光技术，在临床诊断为慢性肾盂肾炎的57例患者中，有49例尿液样本中检测到抗体包被细菌，而11例膀胱炎患者的尿液中未观察到。通过间接免疫荧光技术测定，肾盂肾炎组尿液沉淀物中抗体包被细菌的存在与血清抗体滴度升高之间存在相关性。也发现了血清抗体滴度升高但尿液中无抗体包被细菌的患者，反之亦然。膀胱炎患者针对从尿液中分离出的同源菌株的血清抗体滴度没有升高。考虑到抗体包被细菌的存在和/或血清抗体滴度升高，86.5%的患者可确诊为慢性肾盂肾炎。
