在一项针对处于HIV相关疾病不同临床阶段的同性恋男性的研究中，检测衣原体特异性IgG和IgA血清抗体。

Chlamydia specific IgG and IgA serum antibodies in a study of homosexual men at various clinical stages of HIV related disease.

作者信息

Sarov B, Saah A J, Levy E, Elsana S, Sarov I, Rinaldo C R, Detels R, Phair J, Kaslow R, Gisnberg H

机构信息

Virology Unit, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

出版信息

In Vivo. 1994 Jul-Aug;8(4):593-7.

PMID:7893987

Abstract

The significance of chlamydia serum IgG and IgA antibodies was studied, by immunoperoxidase assay, in 210 homosexual men at various stages of HIV infection. Cross sectional analysis of chlamydia IgG antibodies at a titer of > or = 128 indicated a significantly higher prevalence rate among AIDS patients (27.0%) as compared to asymptomatic HIV seronegatives (6.0%) (p = 0.022). The geometric mean titer (GMT) of IgG antibodies to chlamydia was also significantly higher in AIDS patients (106.4) as compared to HIV seronegatives (58.2) (p = 0.022) and persistently asymptomatic HIV seropositives (51.7) (p = 0.05). Chlamydia IgA antibodies did not differ significantly in prevalence and GMT among the various groups.

摘要

通过免疫过氧化物酶测定法，研究了210名处于不同HIV感染阶段的同性恋男性体内衣原体血清IgG和IgA抗体的意义。对滴度≥128的衣原体IgG抗体进行横断面分析表明，与无症状HIV血清阴性者（6.0%）相比，艾滋病患者中的患病率显著更高（27.0%）（p = 0.022）。与HIV血清阴性者（58.2）（p = 0.022）和持续无症状的HIV血清阳性者（51.7）（p = 0.05）相比，艾滋病患者中衣原体IgG抗体的几何平均滴度（GMT）也显著更高（106.4）。衣原体IgA抗体在不同组之间的患病率和GMT没有显著差异。