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人类海马体中的磁性物质。

Magnetic material in the human hippocampus.

作者信息

Dunn J R, Fuller M, Zoeger J, Dobson J, Heller F, Hammann J, Caine E, Moskowitz B M

机构信息

Department of Geological Sciences, University of California at Santa Barbara 93106.

出版信息

Brain Res Bull. 1995;36(2):149-53. doi: 10.1016/0361-9230(94)00182-z.

DOI:10.1016/0361-9230(94)00182-z
PMID:7895092
Abstract

Magnetic analyses of hippocampal material from deceased normal and epileptic subjects, and from the surgically removed epileptogenic zone of a living patient have been carried out. All had magnetic characteristics similar to those reported for other parts of the brain [6]. These characteristics along with low temperature analysis indicate that the magnetic material is present in a wide range of grain sizes. The low temperature analysis also revealed the presence of magnetite through manifestation of its low temperature transition. The wide range of grain sizes is similar to magnetite produced extracellularly by the GS-15 strain of bacteria and unlike that found in magnetotactic bacteria MV-1, which has a restricted grain size range. Optical microscopy of slices revealed rare 5-10 micron clusters of finer opaque particles, which were demonstrated with Magnetic Force Microscopy to be magnetic. One of these was shown with EDAX to contain AI, Ca, Fe, and K, with approximate weight percentages of 55, 19, 19, and 5, respectively.

摘要

对已故正常人和癫痫患者的海马体材料,以及一名活体患者手术切除的致痫区进行了磁性分析。所有样本的磁性特征均与报道的大脑其他部位相似[6]。这些特征以及低温分析表明,磁性材料存在多种粒径。低温分析还通过其低温转变现象揭示了磁铁矿的存在。粒径范围广泛类似于细菌GS - 15菌株在细胞外产生的磁铁矿,与趋磁细菌MV - 1中发现的不同,后者粒径范围有限。切片的光学显微镜检查显示有罕见的5 - 10微米更细小不透明颗粒簇,磁力显微镜证明这些颗粒具有磁性。其中一个经能谱分析显示含有铝、钙、铁和钾,重量百分比分别约为55%、19%、19%和5%。

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