Minors D S, Akerstedt T, Waterhouse J M
School of Biological Sciences, University of Manchester, Manchester, England.
Chronobiol Int. 1994 Dec;11(6):356-66. doi: 10.3109/07420529409057253.
Deep body temperature and sleep/activity diaries data were recorded during control days and for 6 days after simulated time zone transitions of 8 h to the east (six subjects) or west (seven subjects). Circadian rhythms were assessed by cosinor analysis of both raw data (the conventional method) and purified data (corrected for the effects of sleep and activity). Analysis of raw data gives misleading information about the phase and amplitude of the rhythms due to the masking effects of the exogenous component. Use of purified data indicates that during the process of adjustment after an eastward shift (a) phase changes are more erratic than after a shift to the west; (b) no marked decrease in the amplitude of the rhythms is evident; and (c) no clear evidence exists that the circadian rhythm breaks up temporarily. The masking effect was less after the time zone transition if sleep maintenance was poor.
在对照日以及模拟向东（6名受试者）或向西（7名受试者）跨8个小时时区转换后的6天内，记录深部体温以及睡眠/活动日记数据。通过对原始数据（传统方法）和纯化数据（校正睡眠和活动的影响）进行余弦分析来评估昼夜节律。由于外源性成分的掩盖效应，对原始数据的分析会给出有关节律相位和振幅的误导性信息。使用纯化数据表明，在向东转换后的调整过程中：(a) 相位变化比向西转换后更不稳定；(b) 节律振幅没有明显下降；(c) 没有明确证据表明昼夜节律会暂时中断。如果睡眠维持不佳，时区转换后的掩盖效应会较小。
