Bair H J, Becker W, Schott G, Kühn R H, Wolf F
Department of Nuclear Medicine, University of Erlangen-Nuremberg, Federal Republic of Germany.
Clin Nucl Med. 1995 Jan;20(1):18-21. doi: 10.1097/00003072-199501000-00004.
Scintigraphy with Tc-99m MAG3 is, to date, the most commonly used technique for evaluating separate renal function (SRF). In this study, the performance of this technique is compared to Tc-99m DMSA. A total of 37 patients with various kidney disorders (12 children and 25 adults) underwent both Tc-99m DMSA and Tc-99m MAG 3 scintigraphy. In children and adults of normal weight the correlation coefficient between the two methods was 0.99 (P < 0.001), whereas in individuals who were more than 10% overweight according to Broca, or who had abnormal anatomical positions of the kidneys, the correlation coefficient was 0.82 (P < 0.05). Scintigraphy with Tc-99m DMSA was more accurate in renal parenchyma lesions. These results indicate that Tc-99m DMSA scintigraphy is preferable for the evaluation of SRF in patients who are more than 10% overweight, or have abnormal positions of the kidneys.
迄今为止，锝-99m巯基乙酰三甘氨酸（Tc-99m MAG3）闪烁扫描法是评估分肾功能（SRF）最常用的技术。在本研究中，将该技术的性能与锝-99m二巯丁二酸（Tc-99m DMSA）进行了比较。共有37例患有各种肾脏疾病的患者（12名儿童和25名成人）接受了Tc-99m DMSA和Tc-99m MAG3闪烁扫描。在体重正常的儿童和成人中，两种方法之间的相关系数为0.99（P < 0.001），而根据布罗卡指数超重超过10%或肾脏解剖位置异常的个体，相关系数为0.82（P < 0.05）。Tc-99m DMSA闪烁扫描在肾实质病变方面更准确。这些结果表明，对于超重超过10%或肾脏位置异常的患者，Tc-99m DMSA闪烁扫描更适合用于评估分肾功能。
