Kuraoka S, Orita H, Watanabe T, Gotoh S, Inui K, Washio M
Second Department of Surgery, Yamagata University School of Medicine, Japan.
Kyobu Geka. 1995 Feb;48(2):106-9.
This study was undertaken to compare postsurgical respiratory function after employing cold blood or cold crystalloid cardioplegia during open heart surgery. Fourty patients were divided into two groups for the difference of the cardioplegic solutions. Preoperatively, left ventricular stroke work index (LVSWI) and respiratory function test was evaluated. Postoperatively, A-a DO2 and respiratory index (RI) as functional parameters of oxygenation capacity, LVSWI and dosage of dopamine were monitored at 3, 6, 12, 18, 24 hours after cardiopulmonary bypass and at extubation period. The recovery of respiratory function and cardiac performance were superior in blood cardioplegia with a less accumulation of water in the pulmonary interstitium as a result of hemodilution effect.
本研究旨在比较心脏直视手术中使用冷血或冷晶体心脏停搏液后患者的术后呼吸功能。40例患者因心脏停搏液不同分为两组。术前评估左心室每搏作功指数（LVSWI）和呼吸功能测试。术后，在体外循环后3、6、12、18、24小时以及拔管期监测作为氧合能力功能参数的肺泡-动脉血氧分压差（A-a DO2）和呼吸指数（RI）、LVSWI及多巴胺用量。由于血液稀释作用，冷血心脏停搏液组呼吸功能和心脏功能的恢复更优，肺间质水分蓄积更少。
