Katsumata T, Nemoto S, Nishida H, Hachida M, Endo M, Hashimoto A, Koyanagi H, Kanda K, Tsutsui N
Department of Cardiovascular Surgery, Heart Institute of Japan, Tokyo.
Kyobu Geka. 1995 Mar;48(3):205-8.
Newly-developed catheter for the intraaortic balloon counterpulsation with cardio-renal assist was examined on animal model. The catheter consists of two balloon segments between which the celiac trunk, the superior mesenteric artery and the renal artery are to be placed. Statistical comparison on each hemodynamic element was carried out between the catheter (DBC), conventional single balloon catheter (SBC) of the same balloon volume as DBC and no assist (None) groups. There were no significant changes between SBC and DBC in cardiac output, femoral arterial flow and central venous pressure. Renal arterial flow and urinary output were significantly increased in DBC (None 14.4 +/- 3.9, SBC 22.6 +/- 5.6, DBC 31.0 +/- 6.9 ml/min in renal arterial flow, None 33 +/- 9, SBC 64 +/- 14, DBC 78 +/- 20 ml/h in urinary output, p < or = 0.05). After the remodeling adjust to the human stature, a clinical application would be considered.
在动物模型上对新研发的用于心肾辅助的主动脉内球囊反搏导管进行了检测。该导管由两个球囊段组成，腹腔干、肠系膜上动脉和肾动脉置于这两个球囊段之间。对导管组（DBC）、与DBC球囊容积相同的传统单球囊导管组（SBC）和无辅助组（无）的各项血流动力学指标进行了统计学比较。心输出量、股动脉血流和中心静脉压在SBC和DBC之间无显著变化。DBC组的肾动脉血流和尿量显著增加（肾动脉血流：无辅助组14.4±3.9，SBC组22.6±5.6，DBC组31.0±6.9 ml/min；尿量：无辅助组33±9，SBC组64±14，DBC组78±20 ml/h，p≤0.05）。在根据人体身高进行重塑调整后，将考虑临床应用。
