Juszko J, Marczyńska M, Zarnowska H
Oddziału Okulistycznego Centrum Zdrowia Dziecka, Warszawie.
Klin Oczna. 1994 Aug-Sep;96(8-9):275-80.
In the years 1990-1993 the authors diagnosed and treated 48 children on account of uveitis probably caused by Toxocara canis. This etiology was established in 43 cases based on the characteristic clinical picture and presence of antibodies as determined by the ELISA test for Toxocara in serum, anterior chamber fluid and vitreous. Diagnostic punction of anterior chamber was done in 30 cases (in 18 titres were positive, in 7 higher than in serum), in 3 the level of antibodies were determined in vitreous. In 30 patients Hetrazan, in 3 Hetrazan and Mintezol was applied; in 31 together with Encorton.
vitrectomy and lensectomy were done in 9 children. Improvement of visual acuity was achieved in 41.9% of cases, deterioration in 9.3%. In 33 cases the active signs of vitritis recovered after 2-6 months of treatment, recurrence was observed in 4. An increase of serum titres was found in 10 children in early period after treatment, in 15 they decreased after 6-18 months and in 18 treatment had no influence on the titres level. A relationship was found between the level of titres in anterior chamber and vitreous and the activity and duration of intraocular inflammation.
1990年至1993年期间，作者诊断并治疗了48例可能由犬弓蛔虫引起葡萄膜炎的儿童。根据特征性临床表现以及血清、前房液和玻璃体中犬弓蛔虫酶联免疫吸附试验（ELISA）检测抗体的存在情况，在43例中确定了这种病因。对30例进行了前房诊断性穿刺（18例滴度为阳性，7例高于血清），3例测定了玻璃体中的抗体水平。30例患者应用了海群生，3例应用了海群生和甲苯达唑；31例同时使用了强的松龙。
9例儿童进行了玻璃体切除术和晶状体切除术。41.9%的病例视力得到改善，9.3%的病例视力恶化。33例在治疗2至6个月后葡萄膜炎的活动体征恢复，4例出现复发。10例儿童在治疗后早期血清滴度升高，15例在6至18个月后滴度下降，18例治疗对滴度水平无影响。发现前房和玻璃体中的滴度水平与眼内炎症的活动和持续时间之间存在关联。
