Khella S L, Frost S, Hermann G A, Leventhal L, Whyatt S, Sajid M A, Scherer S S
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia.
Neurology. 1995 Mar;45(3 Pt 1):407-11. doi: 10.1212/wnl.45.3.407.
A patient with mononeuropathy multiplex, hepatitis C viral infection, and mixed cryoglobulinemia had axonal degeneration by EMG and vasculitis of the epineurial vessels on sural nerve biopsy. There was no evidence of viral particles in the nerve by immunofluorescence. Treatment with interferon alfa improved the patient's symptoms and cleared the hepatitis C viral RNA and cryoglobulins from the serum.
一名患有多灶性单神经病、丙型肝炎病毒感染和混合性冷球蛋白血症的患者，肌电图显示有轴索性变性，腓肠神经活检显示神经外膜血管有血管炎。免疫荧光检查未发现神经中有病毒颗粒。使用干扰素α治疗改善了患者症状，并清除了血清中的丙型肝炎病毒RNA和冷球蛋白。
