Seow W K
University of Queensland Dental School, USA.
Pediatr Dent. 1995 Jan-Feb;17(1):26-30.
The present investigation studied dental development in 23 subjects with amelogenesis imperfecta (AI), aged 4.2 to 15.6 years, compared with 46 race-, age-, and sex-matched, healthy, normal controls. The dental ages of the children were assessed from panoramic radiographs using previously established methods. Their chronologic ages at the time of radiographic examination were compared with their dental ages. The results showed that all subjects with AI showed a significant acceleration of dental age of approximately 1.13 +/- 0.78 years compared with control children (P < 0.001). All children were consistently affected regardless of the AI variant. Furthermore, the study found a six-fold increase (26.1 vs. 4.3%) in tendency of AI patients to show impaction of the permanent teeth and associated anomalies such as follicular cysts. These results may be important in planning orthodontic treatment in AI patients, and indicate that they should have early screening to detect these abnormalities.
本研究对23名年龄在4.2至15.6岁之间的釉质发育不全（AI）患者的牙齿发育情况进行了研究，并与46名种族、年龄和性别匹配的健康正常对照者进行了比较。使用先前建立的方法从全景X线片评估儿童的牙龄。将他们在进行X线检查时的实际年龄与其牙龄进行比较。结果显示，与对照儿童相比，所有AI患者的牙龄均显著提前约1.13±0.78岁（P<0.001）。无论AI的变异类型如何，所有儿童均受到一致影响。此外，该研究发现AI患者恒牙阻生及相关异常（如滤泡囊肿）的发生率增加了六倍（26.1%对4.3%）。这些结果对于AI患者正畸治疗方案的制定可能具有重要意义，并表明应对他们进行早期筛查以发现这些异常情况。
