Fiteni I, Ruiz F J, Crusells M J, Sanjoaquin I, Guillen G
Département de Médecine interne, Hôpital clinico-universitaire, Zaragoza, Espagne.
Presse Med. 1995 Feb 11;24(6):309-11.
Focal central nervous system infections, as abscess and empyema, due to Salmonella species are unusual. Even more unusual is the association of cerebral abscess, subdural empyema and epidural abscess we report in the present work. This infection appeared in our patient soon after a brain astrocytoma removal and was treated with cefotaxime and gentamicin during three weeks. In spite of documented genus susceptibility to the drugs the infection relapsed in few days. It was definitely cured with ceftazidime alone for six weeks. Third-generation cephalosporins are good alternatives in uncommon infections and specially in central nervous system salmonellosis, as resistances of this genus to classical drugs are lately increasing.
由沙门氏菌属引起的局灶性中枢神经系统感染，如脑脓肿和脓胸，较为罕见。我们在本研究中报告的脑脓肿、硬膜下脓胸和硬膜外脓肿的联合感染则更为罕见。这种感染在我们的患者脑星形细胞瘤切除后不久出现，并用头孢噻肟和庆大霉素治疗了三周。尽管记录显示该菌属对这些药物敏感，但感染在数天内复发。单独使用头孢他啶治疗六周后感染才得以彻底治愈。第三代头孢菌素在罕见感染中是很好的选择，特别是在中枢神经系统沙门氏菌病中，因为该菌属对传统药物的耐药性最近在增加。
