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[法国的结核病治疗]

[Treatment of tuberculosis in France].

作者信息

Dautzenberg B

机构信息

Service de pneumologie, Groupe hospitalier Pitié-Salpêtrière, Paris.

出版信息

Rev Pneumol Clin. 1994;50(5):256-9.

PMID:7899759
Abstract

In France, the treatment of tuberculosis must take into account both the low rate of multiresistance and the relatively low cost of drugs (the cost of 6 months treatment is about equivalent to the cost of 1 day of hospitalization). A six-month regimen has been recommended in France since 1981. Streptomycin is no longer used routinely. A combination of rifampicin, isoniazid and pyrazinamide is the basis of initial treatment either in as a single medication (Rifater) or taken separately. Ethambutol is added at treatment onset, especially when there was a doubt about resistance. The second phase uses isoniazid and rifampicin, together (Rifanah) or separate.

摘要

在法国,结核病治疗必须兼顾多重耐药率较低以及药物成本相对较低这两个因素(6个月疗程的费用大约相当于1天的住院费用)。自1981年起,法国就推荐采用6个月疗程的治疗方案。链霉素不再常规使用。利福平、异烟肼和吡嗪酰胺联合用药是初始治疗的基础,可以采用单一药物剂型(力排肺疾),也可分别服用。治疗开始时加用乙胺丁醇,尤其是存在耐药疑虑时。第二阶段使用异烟肼和利福平,可联合用药(利福那)或分别服用。

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