Kirichenko A A, Prekina V I, Repinskaia N P, Novichkova Iu N, Ter-Gevondian N M, Vinogradova I V
Ter Arkh. 1994;66(12):23-6.
Serious affections of hemostasis were found in hemostatic examinations involving 67 intermittent claudication patients resistant to longterm vasodilative drugs. A 4-6-month course of tiklid (500 mg daily) induced a significant fall in platelet aggregation and an increase in the blood fibrinolytic activity, decreased foot chilliness, pain while walking. 73% of the patients could cover longer distances without pain complaints.
在对67例对长期血管扩张药物耐药的间歇性跛行患者进行的止血检查中,发现了严重的止血功能紊乱。服用氯苄吡啶(每日500毫克)4至6个月的疗程可使血小板聚集显著下降,血液纤溶活性增加,足部发冷和行走时疼痛减轻。73%的患者能够行走更长距离而无疼痛主诉。