真菌中的葡萄糖阻遏
Glucose repression in fungi.
作者信息
Ronne H
机构信息
Ludwig Institute for Cancer Research, Uppsala Biomedical Center, Sweden.
出版信息
Trends Genet. 1995 Jan;11(1):12-7. doi: 10.1016/s0168-9525(00)88980-5.
PMID:7900189
Abstract
In many organisms, glucose represses genes that are used to metabolize other carbon sources. Work in yeast and filamentous fungi has revealed a mechanism for glucose repression in eukaryotes that is different from that found in bacteria. Zinc finger proteins, such as Mig1 and CREA, that bind GC-boxes play a key role in mediating this response.
摘要
在许多生物体中，葡萄糖会抑制用于代谢其他碳源的基因。对酵母和丝状真菌的研究揭示了真核生物中葡萄糖抑制的一种机制，该机制与细菌中的不同。锌指蛋白，如Mig1和CREA，它们与GC盒结合，在介导这种反应中起关键作用。
Zotero 插件