Nawrot M, Rizzo M
Department of Neurology, University of Iowa College of Medicine, Iowa City 52242.
Vision Res. 1995 Mar;35(5):723-31. doi: 10.1016/0042-6989(94)00168-l.
Although visual motion processing is commonly thought to be mediated solely by visual cortical areas, this human lesion study suggests that the cerebellum also has a role. We found motion direction discrimination deficits in a group of patients with acute midline cerebellar lesions. Unlike normals and patients with hemispheric cerebellar lesions, these patients with midline lesions were unable to discern a global motion vector in a local stochastic motion display. This resembles the perceptual defect reported following cortical area MT lesions in primates. This motion perception deficit may result from damage to a cerebellar mechanism involved in perceptual stabilization. Disruption of this comparator mechanism is sufficient to produce a severe motion perception deficit even though cortical visual processing mechanisms are still intact.
虽然视觉运动处理通常被认为仅由视觉皮层区域介导，但这项人类损伤研究表明小脑也发挥作用。我们在一组急性中线小脑损伤患者中发现了运动方向辨别缺陷。与正常人和半球小脑损伤患者不同，这些中线损伤患者无法在局部随机运动显示中辨别全局运动矢量。这类似于灵长类动物皮层MT区损伤后报道的知觉缺陷。这种运动知觉缺陷可能是由于参与知觉稳定的小脑机制受损所致。即使皮层视觉处理机制仍然完好，这种比较机制的破坏也足以产生严重的运动知觉缺陷。
