Pinto Pereira L M, Clement Y, Telang B V, McFarlane H
West Indian Med J. 1994 Dec;43(4):140-2.
Although the values reported were higher than those reported for Caucasians, differences in dibucaine number for pseudocholinesterase values among the three ethnic groups in Trinidad and Tobago, were not significant. Eight individuals had intermediate dibucaine number values between 40 and 70; one of them was African, 3 were East Indians, and 4 Mixed. Two of the Mixed group were of Portuguese lineage and had significantly lower dibucaine numbers and enzyme concentration. Two sisters of East Indian origin had an inestimable dibucaine number and their pseudocholinesterase values were just detectable, suggesting the presence of a 'silent gene' for pseudocholinesterase. These studies, which are being extended, suggest that the dibucaine number should be estimated prior to succinylcholine administration in patients in Trinidad and Tobago who are at risk of apnoea.
尽管报告的数值高于白种人报告的数值，但特立尼达和多巴哥三个种族群体之间假性胆碱酯酶值的丁卡因值差异并不显著。8个人的丁卡因值处于40至70之间的中等水平；其中1人为非洲裔，3人为东印度裔，4人为混血。混血组中有2人有葡萄牙血统，其丁卡因值和酶浓度显著较低。两名东印度裔姐妹的丁卡因值无法估算，其假性胆碱酯酶值仅可检测到，提示存在假性胆碱酯酶的“沉默基因”。正在进行的这些研究表明，对于有呼吸暂停风险的特立尼达和多巴哥患者，在给予琥珀酰胆碱之前应评估丁卡因值。
