Berg B R, Sarelius I H
Department of Biophysics, School of Medicine and Dentistry, University of Rochester, New York 14642.
Am J Physiol. 1995 Mar;268(3 Pt 2):H1215-22. doi: 10.1152/ajpheart.1995.268.3.H1215.
In striated muscle, capillaries occur as independent network groups. Network architecture was quantitated in cremaster muscle of pentobarbital sodium-anesthetized hamsters in three age groups [51 +/- 1 (SE), 65 +/- 1, and 79 +/- 1 days old]. We observed that networks consist of independent subgroups of capillaries, called modules. Module architecture did not vary significantly with age during maximal dilation (Max, 10(-4) M adenosine): tissue area (A) = 1.87 +/- 0.16, 1.19 +/- 0.13, and 1.81 +/- 0.3 x 10(5) microns 2; total segment length (sigma L) = 3.07 +/- 0.23, 2.15 +/- 0.21, and 3.02 +/- 0.45 x 10(3) microns; and segment number (N) = 14.5 +/- 1.1, 9.9 +/- 1.1, and 12.6 +/- 1.6, at ages 51, 65, and 79 days, respectively. Max module architecture was not different at 65 days of age at a second site of known higher O2 inflow: A = 2.03 +/- 0.32 x 10(5) microns 2; sigma L = 3.07 +/- 0.47 x 10(3) microns; and N = 13.1 +/- 2.1. During control conditions (Rest) there was also no significant difference with age: A = 1.68 +/- 0.18, 1.15 +/- 0.19, and 1.64 +/- 0.24 x 10(5) microns 2; sigma L = 2.31 +/- 0.23, 1.91 +/- 0.33, and 2.82 +/- 0.37 x 10(3) microns; N = 10.2 +/- 1.0, 7.8 +/- 1.3, and 11.0 +/- 1.4, at ages 51, 65, and 79 days, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
在横纹肌中，毛细血管以独立的网络组形式存在。在三个年龄组（51±1（标准误）、65±1和79±1日龄）的戊巴比妥钠麻醉仓鼠的提睾肌中对网络结构进行了定量分析。我们观察到这些网络由称为模块的独立毛细血管亚组组成。在最大扩张（Max，10⁻⁴M腺苷）期间，模块结构随年龄变化不显著：51日龄、65日龄和79日龄时，组织面积（A）分别为1.87±0.16、1.19±0.13和1.81±0.3×10⁵平方微米；总节段长度（∑L）分别为3.07±0.23、2.15±0.21和3.02±0.45×10³微米；节段数（N）分别为14.5±1.1、9.9±1.1和12.6±1.6。在已知氧流入量较高的第二个部位，65日龄时最大模块结构无差异：A = 2.03±0.32×10⁵平方微米；∑L = 3.07±0.47×10³微米；N = 13.1±2.1。在对照条件（静息）下，也未观察到随年龄的显著差异：51日龄、65日龄和79日龄时，A分别为1.68±0.18、1.15±0.19和1.64±0.24×10⁵平方微米；∑L分别为2.31±0.23、1.91±0.33和2.82±0.37×10³微米；N分别为10.2±1.0、7.8±1.3和11.0±1.4。（摘要截断于250字）
