Naito M, Ishiguro H, Fujisawa T, Kurosawa Y
Institute for Comprehensive Medical Science, Fujita Health University, Aichi, Japan.
FEBS Lett. 1993 Nov 1;333(3):271-4. doi: 10.1016/0014-5793(93)80668-k.
Using the polymerase chain reaction, we identified four different homeobox-containing genes in Hydra magnipapillata. Three of them, cnox1-Hm, cnox2-Hm and cnox4-Hm, were equivalent to homeobox genes that had already been identified in other species of cnidarians. cnox5-Hm was a new homeobox gene and was very similar to Mox1 in the mouse. Together with the published data, our results indicate that there are at least eight distinct classes of homeobox genes in cnidarians. These homeobox genes show a maximum of 60 to 77% identity in terms of the amino acid residues in their homeodomains to certain classes of homeobox genes that have been identified in Drosophila.
利用聚合酶链反应，我们在巨型乳头水螅中鉴定出了四个不同的含同源异型框基因。其中三个基因，cnox1-Hm、cnox2-Hm和cnox4-Hm，与已在其他刺胞动物物种中鉴定出的同源异型框基因等同。cnox5-Hm是一个新的同源异型框基因，与小鼠中的Mox1非常相似。结合已发表的数据，我们的结果表明刺胞动物中至少有八类不同的同源异型框基因。这些同源异型框基因的同源结构域中的氨基酸残基与在果蝇中鉴定出的某些类别的同源异型框基因相比，相似度最高可达60%至77%。
