Thompson D F
Department of Pharmacy Practice, Southwestern Oklahoma State University, Weatherford 73096.
J Clin Pharm Ther. 1993 Aug;18(4):255-8. doi: 10.1111/j.1365-2710.1993.tb00584.x.
Drug-induced parotitis is a relatively uncommon adverse drug reaction. Most of the data on drug-induced parotitis consist of isolated case reports with few attempts at rechallenge to confirm the aetiology. Phenylbutazone and oxyphenbutazone have a significant number of reports suggesting that these drugs may be implicated in causing parotitis. Antipsychotics, particularly thioridazine, have been associated with parotitis. Most of these reports relate the anticholinergic oral drying as a predisposing factor in the development of a parotid gland infection. There is inadequate literature on the histamine (H2) receptor blockers, interferon-alpha, doxycycline, trimipramine, nifedipine, methyldopa, nitrofurantoin, nicardipine, isoproterenol or ritodrine to link them as aetiological agents in the development of parotitis.
药物性腮腺炎是一种相对罕见的药物不良反应。关于药物性腮腺炎的大多数数据由孤立的病例报告组成，很少有人尝试再次用药以确认病因。保泰松和羟基保泰松有大量报告表明这些药物可能与腮腺炎的发生有关。抗精神病药物，尤其是硫利达嗪，与腮腺炎有关。这些报告大多将抗胆碱能引起的口腔干燥视为腮腺感染发生的一个易感因素。关于组胺（H2）受体阻滞剂、α干扰素、强力霉素、曲米帕明、硝苯地平、甲基多巴、呋喃妥因、尼卡地平、异丙肾上腺素或利托君，没有足够的文献将它们与腮腺炎发生的病因联系起来。
