Shirasaki T, Munakata M, Akaike N
Department of Neurophysiology, Tohoku University School of Medicine, Sendai, Japan.
Neurosci Lett. 1993 Jul 23;157(2):191-4. doi: 10.1016/0304-3940(93)90734-3.
The metabotropic glutamate (mGlu) response in dissociated rat hippocampal CA1 pyramidal neurons was recorded, using the nystatin-perforated patch-clamp technique. The mGlu response was localized in the ventral site of the hippocampal CA1 region. In both the ventral and dorsal sites of the CA1 region, the current amplitude of the mGlu responses as well as their induction probability (responsiveness) were reduced with development of the brain.
采用制霉菌素穿孔膜片钳技术记录了离体大鼠海马CA1锥体神经元的代谢型谷氨酸（mGlu）反应。mGlu反应定位于海马CA1区的腹侧部位。在CA1区的腹侧和背侧部位，mGlu反应的电流幅度及其诱导概率（反应性）均随着脑的发育而降低。
