Bergolz V M
Neoplasma. 1976;23(5):457-62.
The paper concerns some results in studies on humoral immunity in human and animal leukemia obtained in author's laboratory (1970-1974). The data presented here disclose immunological mechanisms of mice viral leukemogenesis (cytotoxic and blocking antibodies interrelations). The existence of specific humoral immune response in acute leukemia patients was established (immunoglobulins with the properties of antibodies were revealed in 42.6% of patients). Different forms of specific humoral immunity manifestations in different types of leukemia were distinguished (areactive, nonspecific, cytotoxic, blocking and mixed forms.
本文涉及作者实验室(1970 - 1974年)在人类和动物白血病体液免疫研究方面的一些结果。这里呈现的数据揭示了小鼠病毒性白血病发生的免疫机制(细胞毒性抗体和封闭抗体的相互关系)。确定了急性白血病患者中存在特异性体液免疫反应(42.6%的患者体内发现了具有抗体特性的免疫球蛋白)。区分了不同类型白血病中特异性体液免疫表现的不同形式(无反应性、非特异性、细胞毒性、封闭性和混合性形式)。