Falk H L
Oncology. 1976;33(2):77-85. doi: 10.1159/000225110.
In order to understand variations in thresholds to chemical carcinogens, it is important to appreciate, besides the genetic determinants, those many environmental factors which are at play, at all times, modifying the thresholds for chemical carcinogenesis. An understanding of the mechanisms of action of these factors may make it possible to tackle the difficult problem of determining human threshold levels.
为了了解对化学致癌物的阈值变化，除了遗传决定因素外，认识到那些始终在起作用、改变化学致癌阈值的众多环境因素也很重要。了解这些因素的作用机制可能有助于解决确定人类阈值水平这一难题。
