1例用静脉注射克林霉素（克林霉素2-磷酸酯）治疗的亚急性细菌性心内膜炎病例。
A case of subacute bacterial endocarditis treated with parentaral clindamycin (clindamycin 2-phosphate).
作者信息
Freeman R, Roberts D W
出版信息
Postgrad Med J. 1976 Sep;52(611):595-7. doi: 10.1136/pgmj.52.611.595.
Abstract
A case of subacute bacterial endocarditis which was due to an α-haemolytic streptococcus is described. A therapeutic dilemma arose when the patient developed a drug fever to penicillin and was found to be allergic to cephalosporine. Oral clindamycin was used, but had to be abandoned since severe exacerbation of an unsuspected duodenal ulcer resulted. The patient was finally successfully treated with clindamycin-2-phosphate, a new injectable form of the drug, and the success of this therapy is documented.
摘要
本文描述了一例由α溶血性链球菌引起的亚急性细菌性心内膜炎病例。患者出现青霉素药物热且对头孢菌素过敏，从而引发了治疗困境。使用了口服克林霉素，但因引发未被察觉的十二指肠溃疡严重恶化而不得不停用。患者最终使用磷酸克林霉素（该药物的一种新型注射剂型）成功治愈，本文记录了该治疗方法的成功案例。
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本文引用的文献
1
Treatment of infective endocarditis--1973.感染性心内膜炎的治疗——1973年。
Prog Cardiovasc Dis. 1973 Nov-Dec;16(3):275-302. doi: 10.1016/s0033-0620(73)80002-7.
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