Solomon T, Felix J M, Samuel M, Dengo G A, Saldanha R A, Schapira A, Phillips R E
Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford, UK.
Lancet. 1994 Jan 15;343(8890):149-50. doi: 10.1016/s0140-6736(94)90937-7.
We studied the incidence and clinical associations of hypoglycaemia in an acute medical paediatric service in Maputo, Mozambique. Of 603 children, 43 (7.1%) were hypoglycaemic. 16 of these with Plasmodium falciparum malaria had a shorter illness, and a higher incidence of convulsions and focal neurological signs than those with other diagnoses, but were less likely to die. Hypoglycaemia also complicated protein energy malnutrition, pneumonia, encephalitis, intestinal parasite infection, and nephrotic syndrome. 25 of the 603 children died: 7 (16.3%) of 43 with hypoglycaemia and 18 (3.2%) of 560 who were normoglycaemic, (relative risk of death 5.8 [95% confidence interval 2.25 to 14.93]). Hypoglycaemia is common in children in hospital in Mozambique, and should be suspected in any acutely-ill child regardless of the primary disease.
我们在莫桑比克马普托的一家儿科急症医疗服务机构研究了低血糖的发病率及其临床关联。在603名儿童中，43名（7.1%）出现低血糖。其中16名感染恶性疟原虫的儿童病程较短，惊厥和局灶性神经体征的发生率高于其他诊断的儿童，但死亡可能性较小。低血糖也使蛋白质能量营养不良、肺炎、脑炎、肠道寄生虫感染和肾病综合征病情复杂化。603名儿童中有25名死亡：43名低血糖儿童中有7名（16.3%），血糖正常的560名儿童中有18名（3.2%），（死亡相对风险为5.8 [95%置信区间2.25至14.93]）。低血糖在莫桑比克住院儿童中很常见，任何急病儿童都应怀疑有低血糖，无论其原发疾病如何。
