el Sayed F, Viraben R, Bazex J, Gorguet B
Département de Dermatologie, Vénéréologie et Allergologie, CHU Purpan, Toulouse.
Ann Dermatol Venereol. 1993;120(6-7):455-7.
We report two new cases of HIV-1 seropositive subjects who developed porphyria cutanea tarda (PCT). Laboratory examinations revealed a rise of uroporphyrin in the 24-hour urine and a fall of CD4 lymphocytes below 200/mm3 reflecting severe immuno-depression. Treatment with iterative phlebotomy resulted in regression of PCT. In both patients HIV seropositivity was discovered before PCT was diagnosed. Up to now, none of the hypotheses put forward concerning the exact role played by HIV in the genesis of PCT has been confirmed.
我们报告了两例新的HIV-1血清反应阳性且发生迟发性皮肤卟啉症（PCT）的病例。实验室检查显示，24小时尿液中尿卟啉升高，CD4淋巴细胞计数降至200/mm³以下，提示严重免疫抑制。反复放血治疗使PCT病情缓解。两名患者均在PCT诊断之前就已发现HIV血清反应阳性。到目前为止，关于HIV在PCT发病机制中的确切作用所提出的假设均未得到证实。
