Horton E W, Poyser N L
Physiol Rev. 1976 Oct;56(4):595-651. doi: 10.1152/physrev.1976.56.4.595.
To summarize luteal function during pregnancy briefly, there are physiological processes initiated by the embryo and/or conceptus in early pregnancy that serve to prolong the life-span of the corpus luteum. Some of these processes are well defined, but others remain more obscure. The corpus luteum is maintained in a functional state throughout pregnancy (at least in those species described in this review), even though in several species progesterone production by the corpus luteum is not required after the first third of the gestational period. The cessation of secretory function by the corpus luteum of pregnancy at the end of gestation is apparently actively induced. There is evidence in some species (especially the goat) that this is due to PGF2alpha released from the uterus or placenta. It is concluded that the occurrence of luteal regression in several species of mammal can be attributed to the physiological release of PGF2alpha from both the pregnant and nonpregnant uterus.
妊娠早期，胚胎和/或孕体启动了一些生理过程，以延长黄体的寿命。其中一些过程已明确，但其他过程仍较模糊。整个孕期黄体都维持在功能状态（至少在本综述所描述的物种中如此），尽管在几个物种中，妊娠三分之一期过后，黄体分泌孕酮并非必需。妊娠末期孕期黄体分泌功能的停止显然是被主动诱导的。在一些物种（尤其是山羊）中有证据表明，这是由于子宫或胎盘释放的前列腺素F2α所致。得出的结论是，几种哺乳动物黄体退化的发生可归因于妊娠子宫和未妊娠子宫中前列腺素F2α的生理性释放。
