Human type I and II IMP dehydrogenases as drug targets.

Suppr

超能文献

作者信息

Natsumeda Y, Carr S F

机构信息

Institute of Biochemistry and Cell Biology, Syntex Discovery Research, Palo Alto, California 94303.

出版信息

Ann N Y Acad Sci. 1993 Nov 30;696:88-93. doi: 10.1111/j.1749-6632.1993.tb17144.x.

DOI:10.1111/j.1749-6632.1993.tb17144.x

PMID:7906497

Abstract

摘要

相似文献

Human type I and II IMP dehydrogenases as drug targets.

Ann N Y Acad Sci. 1993 Nov 30;696:88-93. doi: 10.1111/j.1749-6632.1993.tb17144.x.

Characterization of human type I and type II IMP dehydrogenases.

J Biol Chem. 1993 Dec 25;268(36):27286-90.

Molecular characterization of IMP dehydrogenase in acquired resistance to mycophenolic acid.

Adv Exp Med Biol. 1994;370:725-8. doi: 10.1007/978-1-4615-2584-4_151.

Inosine 5'-monophosphate dehydrogenase.

Adv Enzymol Relat Areas Mol Biol. 2009;76:1-53.

Recombinant human inosine monophosphate dehydrogenase type I and type II proteins. Purification and characterization of inhibitor binding.重组人 I 型和 II 型肌苷单磷酸脱氢酶蛋白。抑制剂结合的纯化与表征。

Biochem Pharmacol. 1995 May 11;49(9):1323-9. doi: 10.1016/0006-2952(95)00026-v.

Gene amplification and dual point mutations of mouse IMP dehydrogenase associated with cellular resistance to mycophenolic acid.

Biochim Biophys Acta. 1994 Mar 1;1217(2):156-62. doi: 10.1016/0167-4781(94)90029-9.

Overexpression of a cloned IMP dehydrogenase gene of Candida albicans confers resistance to the specific inhibitor mycophenolic acid.白色念珠菌克隆的肌苷-5'-单磷酸脱氢酶基因的过表达赋予了对特异性抑制剂霉酚酸的抗性。

J Bacteriol. 1997 Apr;179(7):2331-8. doi: 10.1128/jb.179.7.2331-2338.1997.

Detection of the mycophenolate-inhibited form of IMP dehydrogenase in vivo.体内霉酚酸抑制形式的肌苷-5'-单磷酸脱氢酶的检测。

Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12171-6. doi: 10.1073/pnas.0403341101. Epub 2004 Aug 3.

Regulation of an IMP dehydrogenase gene and its overexpression in drug-sensitive transcription elongation mutants of yeast.酵母药物敏感型转录延伸突变体中肌苷一磷酸脱氢酶基因的调控及其过表达

J Biol Chem. 2001 Aug 31;276(35):32905-16. doi: 10.1074/jbc.M105075200. Epub 2001 Jul 5.

Species-specific inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid.霉酚酸对肌苷5'-单磷酸脱氢酶的种属特异性抑制作用。

Biochemistry. 1999 Nov 16;38(46):15388-97. doi: 10.1021/bi991558q.

引用本文的文献

LC-MS/MS method for quantitation of mycophenolic acid, mycophenolic acid acyl-glucuronide, and 7-O-mycophenolic acid glucuronide in serum.用于定量血清中霉酚酸、霉酚酸酰基葡萄糖醛酸化物和7-O-霉酚酸葡萄糖醛酸化物的液相色谱-串联质谱法。

Clin Mass Spectrom. 2017 Jul 10;3:41-48. doi: 10.1016/j.clinms.2017.07.001. eCollection 2017 Jan.

Successful Treatment of Systemic Sclerosis-related Pericarditis with Mycophenolate Mofetil and Low-dose Prednisolone.霉酚酸酯和低剂量泼尼松龙成功治疗系统性硬化症相关心包炎。

Intern Med. 2022 Oct 15;61(20):3125-3130. doi: 10.2169/internalmedicine.8844-21. Epub 2022 Mar 12.

High expression of IMPDH2 is associated with aggressive features and poor prognosis of primary nasopharyngeal carcinoma.IMPdh2 的高表达与原发性鼻咽癌的侵袭性特征和不良预后相关。

Sci Rep. 2017 Apr 7;7(1):745. doi: 10.1038/s41598-017-00887-1.

Pharmacological targeting of allergen-specific T lymphocytes.过敏原特异性 T 淋巴细胞的药物靶向治疗。

Immunol Lett. 2017 Sep;189:27-39. doi: 10.1016/j.imlet.2017.03.010. Epub 2017 Mar 18.

Pragmatic Treatment of Patients With Systemic Lupus Erythematosus With Rituximab: Long-Term Effects on Serum Immunoglobulins.利妥昔单抗对系统性红斑狼疮患者的实用治疗：对血清免疫球蛋白的长期影响

Arthritis Care Res (Hoboken). 2017 Jun;69(6):857-866. doi: 10.1002/acr.22993. Epub 2017 Apr 24.

In Vitro Influence of Mycophenolic Acid on Selected Parameters of Stimulated Peripheral Canine Lymphocytes.霉酚酸对体外刺激的犬外周淋巴细胞选定参数的影响

PLoS One. 2016 May 3;11(5):e0154429. doi: 10.1371/journal.pone.0154429. eCollection 2016.

Osteoclast Differentiation Is Impaired in a Subgroup of SLE Patients and Correlates Inversely with Mycophenolate Mofetil Treatment.破骨细胞分化在一部分系统性红斑狼疮患者中受损，且与霉酚酸酯治疗呈负相关。

Int J Mol Sci. 2015 Aug 12;16(8):18825-35. doi: 10.3390/ijms160818825.

Overexpression of inosine 5'-monophosphate dehydrogenase type II mediates chemoresistance to human osteosarcoma cells.肌苷 5'-单磷酸脱氢酶 II 型的过表达介导人骨肉瘤细胞对化疗的耐药性。

PLoS One. 2010 Aug 16;5(8):e12179. doi: 10.1371/journal.pone.0012179.

IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations.硫唑嘌呤治疗的炎症性肠病患者的肌苷-5'-单磷酸脱氢酶活性——与硫嘌呤甲基转移酶活性及代谢物浓度的关系

Br J Clin Pharmacol. 2008 Jan;65(1):69-77. doi: 10.1111/j.1365-2125.2007.02985.x. Epub 2007 Jul 27.

Mycophenolate mofetil inhibits differentiation, maturation and allostimulatory function of human monocyte-derived dendritic cells.霉酚酸酯抑制人单核细胞衍生树突状细胞的分化、成熟和同种异体刺激功能。

Clin Exp Immunol. 2003 Oct;134(1):63-9. doi: 10.1046/j.1365-2249.2003.02269.x.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验