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Isolation and characterisation of five new anonymous X-specific probes. One of them detecting a TaqI RFLP.

作者信息

Belhadj-Kacem N, Heuertz S, Hors-Cayla M C, Saidi-Mehtar N, Sefiani A

机构信息

INSERM U12, Hôpital des Enfants-Malades, Paris, France.

出版信息

Ann Genet. 1993;36(3):139-43.

PMID:7906932
Abstract

The authors isolated five single-copy X-specific probes from an X-enriched library. These probes were regionally localized on the X chromosome by using somatic hybrid cell lines obtained from patients carrying different X-autosome translocations. Three clones were located between Xq23 and Xq26, the two others were mapped between Xp21 and Xp11.2. Analyses with different restriction enzymes indicated that one of them detects a TaqI polymorphism with a polymorphism information content (PIC) of 0.28.

摘要

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