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遗传物质捐赠:精子、卵母细胞、胚胎前体。

Genetic material donation: sperm, oocyte, pre-embryo.

作者信息

Schenker J G

机构信息

Department of Obstetrics and Gynecology, Hadassah University Hospital, Jerusalem, Israel.

出版信息

Int J Gynaecol Obstet. 1993 Dec;43(3):247-55. doi: 10.1016/0020-7292(93)90512-u.

DOI:10.1016/0020-7292(93)90512-u
PMID:7907034
Abstract

Genetic material donation has become an integral part of the management of infertility. Sperm, oocyte and pre-embryo donation are medical and technical successful procedures, undertaken to deliberately procure the creation of a child. By application of the modern assisted reproductive technologies (ART), it is the adult's interests which are upheld. This does not necessarily imply that those interests apply also to the resulting offspring. Therefore, practice of genetic material donation raises ethical, legal, religious and social issues, which are discussed. The practice of gametes and pre-embryo donation is opposed by the main religions. The medical problems are related mainly to selection of donors, evaluation of recipients and quality control of the genetic material. The relationship between the biological and social parents and safeguarding the interest of the offspring, may be resolved by legislation pertaining to the individual country. Sperm and pre-embryo banks should be subjected to licensing and should not be run by a commercial system. The donated genetic material should not be used to extend the natural reproductive life span. By practicing sperm, oocyte and pre-embryo donation the medical profession and society should consider not only the interests of the infertile couple but the interests of the offspring as well.

摘要

遗传物质捐赠已成为不孕症治疗不可或缺的一部分。精子、卵子和胚胎前体捐赠是医学和技术上成功的程序,旨在有意促成孩子的诞生。通过应用现代辅助生殖技术(ART),维护的是成年人的利益。但这并不一定意味着这些利益也适用于由此产生的后代。因此,遗传物质捐赠引发了伦理、法律、宗教和社会问题,本文对此进行了讨论。主要宗教反对配子和胚胎前体捐赠行为。医学问题主要涉及供体的选择、受体的评估以及遗传物质的质量控制。生物学父母和社会父母之间的关系以及对后代利益的保护,可通过各国的相关立法来解决。精子库和胚胎前体库应获得许可,且不应由商业系统运营。捐赠的遗传物质不应被用于延长自然生殖寿命。通过实施精子、卵子和胚胎前体捐赠,医学界和社会不仅应考虑不孕夫妇的利益,还应考虑后代的利益。

相似文献

1
Genetic material donation: sperm, oocyte, pre-embryo.遗传物质捐赠:精子、卵母细胞、胚胎前体。
Int J Gynaecol Obstet. 1993 Dec;43(3):247-55. doi: 10.1016/0020-7292(93)90512-u.
2
Pre-embryo donation: ethical and legal aspects.胚胎前捐赠:伦理与法律问题
Int J Gynaecol Obstet. 1998 Jan;60(1):51-7. doi: 10.1016/s0020-7292(97)00231-2.
3
Sperm, oocyte, and pre-embryo donation.精子、卵母细胞和胚胎前体捐赠。
J Assist Reprod Genet. 1995 Sep;12(8):499-508. doi: 10.1007/BF02212912.
4
Ethical and legal issues in human embryo donation.人类胚胎捐赠中的伦理和法律问题。
Fertil Steril. 1995 Nov;64(5):885-94. doi: 10.1016/s0015-0282(16)57897-2.
5
The donation of gametes is possible without paying donors: experience of the French CECOS Federation. Centre for the cryopreservation of eggs and semen.不向捐赠者支付报酬也可以进行配子捐赠:法国生育与生殖医学中心联合会的经验。卵子和精液冷冻保存中心。
Hum Reprod. 1998 May;13(5):1129-30. doi: 10.1093/humrep/13.5.1129.
6
Disclosure behaviour and intentions among 111 couples following treatment with oocytes or sperm from identity-release donors: follow-up at offspring age 1-4 years.身份公开供精或供卵治疗后 111 对夫妇的披露行为和意向:随访至子女 1-4 岁。
Hum Reprod. 2012 Oct;27(10):2998-3007. doi: 10.1093/humrep/des285. Epub 2012 Aug 1.
7
Infertility evaluation and treatment according to Jewish law.根据犹太律法进行的不孕症评估与治疗。
Eur J Obstet Gynecol Reprod Biol. 1997 Feb;71(2):113-21. doi: 10.1016/s0301-2115(96)02621-8.
8
Current European laws on gamete donation.欧洲现行的配子捐赠法律。
Hum Reprod. 1998 May;13 Suppl 2:105-34.
9
Attitudes towards gamete donation among couples undergoing in vitro fertilization.接受体外受精的夫妇对配子捐赠的态度。
Br J Obstet Gynaecol. 1991 Apr;98(4):351-6. doi: 10.1111/j.1471-0528.1991.tb13424.x.
10
2006 Guidelines for Gamete and Embryo Donation.2006年配子与胚胎捐赠指南。
Fertil Steril. 2006 Nov;86(5 Suppl 1):S38-50. doi: 10.1016/j.fertnstert.2006.06.001.

引用本文的文献

1
Zoroastrians support oocyte and embryo donation program for infertile couples.琐罗亚斯德教徒支持为不孕夫妇开展的卵母细胞和胚胎捐赠项目。
J Reprod Infertil. 2014 Oct;15(4):222-8.