人类10号染色体着丝粒周围区域的多区间物理图谱。
A multiple interval physical map of the pericentromeric region of human chromosome 10.
作者信息
Tunnacliffe A, Jackson M S, Gardner E, Love D R, Moore J K, Mole S E, Mulligan L M, Graham A, Finocchiaro G, Orstavik S
机构信息
Department of Pathology, University of Cambridge, UK.
出版信息
Hum Genet. 1994 Mar;93(3):313-8. doi: 10.1007/BF00212029.
Five intervals in the pericentromeric region of human chromosome 10 have been defined using a panel of somatic cell hybrids carrying portions of the chromosome. The map positions of twelve markers, consisting of four genes and eight anonymous DNA segments, have been localized by assignment to one of the five intervals. Several other markers could be placed in specific intervals by genetic linkage to assigned loci. When previously published data are incorporated, the summary map of the pericentromeric region encompasses thirty-two loci in bands 10p11.2-q11.2.
利用一组携带人类10号染色体部分片段的体细胞杂种，已确定了该染色体着丝粒周围区域的五个区间。由四个基因和八个匿名DNA片段组成的12个标记的图谱位置，已通过指定到五个区间之一而定位。通过与已定位基因座的遗传连锁，还可将其他几个标记置于特定区间。纳入先前发表的数据后，着丝粒周围区域的汇总图谱涵盖了10p11.2-q11.2带中的32个基因座。
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