Ozel M, Diringer H
Robert Koch-Institut des Bundesgesundheltsamtes, Berlin, FGR.
Lancet. 1994 Apr 9;343(8902):894-5. doi: 10.1016/s0140-6736(94)90010-8.
The scrapie model in hamsters has been used to search for the agents that cause Creutzfeldt-Jakob disease in man and similar transmissible encephalopathies in animals. We found structures that are extraordinarily small for a virus, but exhibit viral structural properties in negatively stained samples, by electron microscopy in fractions containing scrapie-associated fibrils.
