Pharmacological evidence for full agonist activity of abecarnil at certain GABAA receptors.
作者信息
Serra M, Ghiani C A, Motzo C, Biggio G
机构信息
Department of Experimental Biology Bernardo Loddo, University of Cagliari, Italy.
出版信息
Psychopharmacol Ser. 1993;11:62-78. doi: 10.1007/978-3-642-78451-4_6.
PMID:7908434
Abstract
摘要
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Pharmacological evidence for full agonist activity of abecarnil at certain GABAA receptors.阿贝卡尼在某些GABAA受体上具有完全激动剂活性的药理学证据。
Psychopharmacol Ser. 1993;11:62-78. doi: 10.1007/978-3-642-78451-4_6.
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Abecarnil is a full agonist at some, and a partial agonist at other recombinant GABAA receptor subtypes.阿贝卡尼对某些重组GABAA受体亚型是完全激动剂，而对其他亚型则是部分激动剂。
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引用本文的文献
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Abecarnil, a beta-carboline derivative, does not exhibit anticonvulsant tolerance or withdrawal effects in mice.阿贝卡尼，一种β-咔啉衍生物，在小鼠中不表现出抗惊厥耐受性或戒断效应。
Naunyn Schmiedebergs Arch Pharmacol. 1996 Nov;354(5):612-7. doi: 10.1007/BF00170836.
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