阿贝卡尼对某些重组GABAA受体亚型是完全激动剂，而对其他亚型则是部分激动剂。 - Suppr

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超能文献

Abecarnil is a full agonist at some, and a partial agonist at other recombinant GABAA receptor subtypes.

作者信息

Pribilla I, Neuhaus R, Huba R, Hillmann M, Turner J D, Stephens D N, Schneider H H

机构信息

Research Laboratories of Schering AG, Berlin, Germany.

出版信息

Psychopharmacol Ser. 1993;11:50-61. doi: 10.1007/978-3-642-78451-4_5.

DOI:10.1007/978-3-642-78451-4_5

PMID:7908433

Abstract

摘要

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Abecarnil is a full agonist at some, and a partial agonist at other recombinant GABAA receptor subtypes.阿贝卡尼对某些重组GABAA受体亚型是完全激动剂，而对其他亚型则是部分激动剂。

Psychopharmacol Ser. 1993;11:50-61. doi: 10.1007/978-3-642-78451-4_5.

Pharmacological evidence for full agonist activity of abecarnil at certain GABAA receptors.阿贝卡尼在某些GABAA受体上具有完全激动剂活性的药理学证据。

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Abecarnil, a beta-carboline derivative, does not exhibit anticonvulsant tolerance or withdrawal effects in mice.阿贝卡尼，一种β-咔啉衍生物，在小鼠中不表现出抗惊厥耐受性或戒断效应。

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