Schröder U, Waller V, Kaliebe T, Agathos M, Breit R
Dermatologische und Allergologische Abteilung, Ludwig-Maximilians-Universität München.
Hautarzt. 1994 Jan;45(1):29-33. doi: 10.1007/pl00013251.
We report a 34-year-old homosexual man who developed a maculopapular, non-itchy exanthema mainly on the trunk in addition to fever up to 39.8 degrees C, general malaise, arthralgias, generalized enlargement of the lymph nodes, watery diarrhoea and weight loss. The patient was in an acute phase of the HIV infection according to standards of WHO and CDC (i.e. acute infection with duration from 3 days to 3 weeks with occasional mononucleosis-like symptoms and positive antibody tests). We documented the seroconversion from HIV-negativity to HIV-positivity 15 days after the onset of the acute illness, concomitant with the resolution of the clinical symptoms. Haematological changes were monitored during the conversion. The infection with HIV-1 was shown by the reduction of T4 helper cells (262/microliters) and the inversion of the CD4:CD8 ratio (< 0.5 during seroconversion). The patient also developed generalized candidiasis owing to the acute immunodeficiency.
我们报告了一名34岁的同性恋男性，他除了体温高达39.8摄氏度、全身不适、关节痛、全身淋巴结肿大、水样腹泻和体重减轻外，还出现了主要位于躯干的斑丘疹、不痒的皮疹。根据世界卫生组织（WHO）和美国疾病控制与预防中心（CDC）的标准，该患者处于HIV感染急性期（即急性感染，病程从3天至3周，偶有单核细胞增多症样症状，抗体检测呈阳性）。我们记录了急性疾病发作15天后患者从HIV阴性血清转化为HIV阳性血清，同时临床症状消退。在血清转化过程中监测了血液学变化。HIV-1感染表现为T4辅助细胞减少（262/微升）以及CD4:CD8比值倒置（血清转化期间<0.5）。由于急性免疫缺陷，该患者还出现了全身性念珠菌病。
