Drake S, Swift W, Hall W, Ross M
National Drug and Alcohol Research Centre, University of New South Wales, Kensington, Australia.
Drug Alcohol Depend. 1993 Dec;34(1):67-70. doi: 10.1016/0376-8716(93)90047-t.
Methadone maintenance clients who used benzodiazepines were compared with other methadone maintenance clients on a range of drug use and psychosocial treatment outcome measures. Despite being on higher methadone doses, benzodiazepine users were more likely to have recently injected, to have used cocaine and amphetamines, to have borrowed or lent used needles and syringes, and to have reported polydrug use in the preceding month. Benzodiazepine users also exhibited higher levels of psychopathology and social dysfunction than other methadone maintenance clients. It is concluded that benzodiazepine-using methadone maintenance clients are a dysfunctional subgroup of the methadone population, who may require more clinical intervention than other clients.
将使用苯二氮䓬类药物的美沙酮维持治疗患者与其他美沙酮维持治疗患者在一系列药物使用和心理社会治疗结果指标上进行了比较。尽管苯二氮䓬类药物使用者服用的美沙酮剂量更高，但他们近期更有可能注射过毒品、使用过可卡因和苯丙胺、借用过或出借过用过的针头和注射器，并且在前一个月报告有多种药物使用情况。与其他美沙酮维持治疗患者相比，苯二氮䓬类药物使用者还表现出更高水平的精神病理学和社会功能障碍。得出的结论是，使用苯二氮䓬类药物的美沙酮维持治疗患者是美沙酮人群中功能失调的亚组，可能比其他患者需要更多的临床干预。
