Glusac E J, Barr R J, Everett M A, Pitha J, Santa Cruz D J
Department of Dermatology, University of California, Irvine.
Am J Surg Pathol. 1994 Jun;18(6):583-90.
Epithelioid cell histiocytoma is a recently recognized lesion that is considered to be a variant of cutaneous fibrous histiocytoma (dermatofibroma). Ten cases are presented, including their light microscopic, immunohistochemical, and ultrastructural features. Eight of the cases are similar to those previously reported, presenting as elevated nodules arising on the extremities and composed of epithelioid histiocytes with overlying epidermal effacement. Two of the cases were composed of cells with the same morphologic and immunohistochemical characteristics as typical epithelioid cell histiocytoma, including factor XIIIa positivity, but these arose in the reticular dermis and exhibited prominent cellularity.
上皮样细胞组织细胞瘤是一种最近才被认识的病变，被认为是皮肤纤维组织细胞瘤（皮肤纤维瘤）的一种变体。本文报告了10例病例，包括其光镜、免疫组化和超微结构特征。其中8例与先前报道的病例相似，表现为四肢出现的隆起性结节，由上皮样组织细胞组成，表面覆盖的表皮消失。另外2例由具有与典型上皮样细胞组织细胞瘤相同形态学和免疫组化特征的细胞组成，包括因子XIIIa阳性，但这些病例发生于网状真皮层，细胞丰富明显。
