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伤口感染率:定义及出院后伤口监测的重要性

Wound infection rates: the importance of definition and post-discharge wound surveillance.

作者信息

Byrne D J, Lynch W, Napier A, Davey P, Malek M, Cuschieri A

机构信息

Department of Surgery, Ninewells Hospital and Medical School, Dundee, Scotland.

出版信息

J Hosp Infect. 1994 Jan;26(1):37-43. doi: 10.1016/0195-6701(94)90077-9.

Abstract

The importance of definition and post-discharge wound surveillance on reported wound infection rates have been studied, using data taken from a prospective, randomized, placebo-controlled, double-blind trial of the effect of whole body disinfection on postoperative wound infection rates. All patients admitted for an elective clean or potentially contaminated surgical procedure over a 32-month period were recruited into the study. Of the 3733 patients recruited, 3466 completed the study. Wound infection (which is defined for this study) is the main outcome that was examined. The effect of careful post-discharge follow-up of patients to look for wound infections was analysed for age, wound type and presence or absence of a drain. Sixty percent of postoperative wound infections occurred after discharge. A rising wound infection rate with increasing age was observed in the in-hospital cohort whereas the incidence of outpatient wound infections declined with age. This finding is attributed to the longer in-hospital stay encountered in patients above 50 years old (median, 3 vs. 5 days, P < 0.00001). Although clean operations had a significantly lower in-hospital infection rate, potentially contaminated procedures had a lower outpatient infection rate. A similar picture was observed in other subgroups of operations including horizontal versus vertical wounds and use of drains. When assessing reported wound infection rates, the definition of wound infection used and the extent of follow-up must be known to enable accurate assessment of the results.

摘要

利用一项关于全身消毒对术后伤口感染率影响的前瞻性、随机、安慰剂对照、双盲试验的数据,研究了定义和出院后伤口监测对报告的伤口感染率的重要性。在32个月期间,所有因择期清洁或可能污染的外科手术入院的患者均被纳入该研究。在招募的3733名患者中,3466名完成了研究。伤口感染(本研究对此有定义)是主要的研究结果。针对年龄、伤口类型以及是否有引流管,分析了对患者进行仔细的出院后随访以查找伤口感染的效果。60%的术后伤口感染发生在出院后。在住院队列中,观察到随着年龄增长伤口感染率上升,而门诊伤口感染的发生率则随年龄下降。这一发现归因于50岁以上患者住院时间更长(中位数,3天对5天,P<0.00001)。尽管清洁手术的住院感染率显著较低,但可能污染的手术门诊感染率较低。在其他手术亚组中也观察到了类似情况,包括横切口与纵切口以及是否使用引流管。在评估报告的伤口感染率时,必须了解所使用的伤口感染定义以及随访范围,以便准确评估结果。

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