Sams W M
Ann Allergy. 1976 Oct;37(4):255-63.
Pemphigus is an erosive disease of the skin and mucous membranes, characterized by intraepidermal blisters, acantholysis of epidermal cells and a serum antibody directed to an antigen at the intercellular space. Pemphigoid is a bullous disease primarily of the skin and usually seen in older individuals. The blister forms beneath the epidermis and the serum antibody is directed to the basement membrane zone. Both diseases may require systemic corticosteroids or cytotoxic agents for control.
天疱疮是一种皮肤和黏膜的糜烂性疾病，其特征为表皮内水疱、表皮细胞棘层松解以及针对细胞间间隙抗原的血清抗体。类天疱疮是一种主要累及皮肤的大疱性疾病，常见于老年人。水疱在表皮下形成，血清抗体针对基底膜带。这两种疾病都可能需要使用全身性皮质类固醇或细胞毒性药物来控制。
