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烧伤研究:十五、局部脂质在治疗人类烧伤中的应用。

Studies in burns: XV. Use of a topical lipid in treating human burns.

作者信息

Jelenko C, McKinley J C

出版信息

Am Surg. 1976 Nov;42(11):838-48.

PMID:791038
Abstract

Sixty patients were selected from the 24-month burn population admitted to the Medical College of Georgia. Selection was on the basis of age, size of burn, and survival beyond 120 hours. Thirty-one of these patients were treated with ethyl linoleate agent (hELate) in addition to the modalities we routinely use for burn care. hELate was applied in a dose of 25 mg/kg only once in the period after burn. Significant pain relief and enhancement of wound healing (with return of hair and pigment) occurred in the hELate-treated patient. Less narcotic was needed, fewer grafts and reconstructive procedures were required, and hospital stay was reduced significantly. It is suggested that hELate is a safe and useful adjunctive to burn care.

摘要

从佐治亚医学院收治的24个月内烧伤患者中选取了60例。入选标准为年龄、烧伤面积和烧伤120小时后的存活情况。其中31例患者除了接受我们常规用于烧伤护理的方法外,还接受了亚油酸乙酯制剂(hELate)治疗。hELate仅在烧伤后的一段时间内以25mg/kg的剂量给药一次。接受hELate治疗的患者疼痛明显减轻,伤口愈合加快(毛发和色素恢复)。所需的麻醉剂减少,所需的移植和重建手术减少,住院时间显著缩短。提示hELate是烧伤护理的一种安全有效的辅助手段。

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