Lauer G, Stegmüller-Koenemund U
Psychiatrische Universitätsklinik, Heidelberg.
Psychiatr Prax. 1994 Mar;21(2):70-3.
The relationships of subjective quality of life in nine domains and negative symptoms, duration of illness, dosage of a neuroleptic and neuroleptic side-effects are investigated in 30 chronic schizophrenic patients. Negative symptoms show negative correlations with four domains (safety, social relations, health, leisure), duration of illness with three domains (health, leisure, living situation). Whereas the dosage of a neuroleptic relates to safety only, neuroleptic side-effects correlate with five domains (social relations, health, safety, living situation, work and employment). The results are discussed in the light of clinical experience and former empirical studies. Proposals for further research are presented.
对30例慢性精神分裂症患者主观生活质量九个领域与阴性症状、病程、抗精神病药物剂量及抗精神病药物副作用之间的关系进行了研究。阴性症状与四个领域(安全、社会关系、健康、休闲)呈负相关,病程与三个领域(健康、休闲、生活状况)呈负相关。而抗精神病药物剂量仅与安全相关,抗精神病药物副作用与五个领域(社会关系、健康、安全、生活状况、工作与就业)相关。根据临床经验和以往的实证研究对结果进行了讨论。并提出了进一步研究的建议。