Fontaine E, Barthelemy Y, Gagnadoux M F, Cukier J, Broyer M, Beurton D
Service de Chirurgie Urologique, Hôpital Ambroise Paré (Paris-Ouest), Boulogne.
Prog Urol. 1994 Apr;4(2):193-205.
In a series of 715 renal transplantations performed between 1973 and 1989, 72 cases of renal artery stenosis (RAS) in 69 children (9.7%) were managed at Hôpital Necker Enfants Malades. Forty cases of RAS were treated exclusively by antihypertensive drugs. A good result was obtained in 82.5% of cases. Thirty three transluminal angioplasties (TLA) were performed in 23 children with 26 RAS. A good clinical result was obtained in 15 children with a total of 17 stenoses, corresponding to a success rate of 65%. Transluminal dilatation of anastomotic stenoses always failed. There were no cases of transplant thrombosis. Eleven RAS were operated, including 5 after failure of TLA. Eight patients (73%) obtained a clinical improvement. There were 2 postoperative thromboses. Antihypertensive treatment must be administered in every case. If medical treatment fails, and with the exception of anastomotic stenoses, TLA should be the first-line procedure, while surgery is reserved for failures of TLA and for anastomotic stenoses.
在1973年至1989年期间进行的715例肾移植手术中,巴黎内克尔儿童医院处理了69例儿童(9.7%)的72例肾动脉狭窄(RAS)。40例RAS仅接受了降压药物治疗。82.5%的病例取得了良好效果。对23例患有26处RAS的儿童进行了33次腔内血管成形术(TLA)。15例患有总共17处狭窄的儿童取得了良好的临床效果,成功率为65%。吻合口狭窄的腔内扩张总是失败。没有移植血栓形成的病例。对11例RAS进行了手术,其中5例是在TLA失败后进行的。8例患者(73%)临床症状改善。有2例术后血栓形成。每种情况都必须进行降压治疗。如果药物治疗失败,除了吻合口狭窄外,TLA应作为一线治疗方法,而手术则留用于TLA失败和吻合口狭窄的情况。