Izumi H, Karita K
Department of Physiology, Tohoku University School of Dentistry, Sendai, Japan.
Am J Physiol. 1994 May;266(5 Pt 2):R1517-22. doi: 10.1152/ajpregu.1994.266.5.R1517.
Electrical stimulation of the peripheral and central cut ends of the chorda tympani nerve (CTN) caused an increase in ipsilateral tongue blood flow in anesthetized cats. Both blood flow increases were markedly reduced by pretreatment with the autonomic ganglionic blocker hexamethonium (1.0 mg/kg). Electrical stimulation of the central cut ends of the CTN, inferior alveolar nerve, and vagus nerve as well as of the upper buccal gingiva also caused the vasodilator responses in the sympathectomized cat tongue. These vasodilatations were notably reduced by hexamethonium pretreatment, and were almost completely abolished by the section of the distal lingual nerve (DLN) and the lingual nerve proper but not by section of the CTN. The present data suggest that the parasympathetic vasodilator fibers in the CTN are not involved in somatoautonomic reflex vasodilatation in the cat tongue and that the major part of the somatoautonomic reflex vasodilator response is mediated by parasympathetic fibers running together with the trigeminal portion of the DLN as vasodilator fibers in the cat tongue. This also implies that there are two groups of parasympathetic vasodilator fibers, that is, one originates from the CTN (the facial nerve) and other from the trigeminal portion of the DLN (probably via the glossopharyngeal nerve).
电刺激鼓索神经（CTN）的外周和中枢切断端可使麻醉猫同侧舌血流量增加。两种血流量增加均因预先使用自主神经节阻滞剂六甲铵（1.0mg/kg）而显著降低。电刺激CTN的中枢切断端、下牙槽神经、迷走神经以及上颊牙龈也可引起交感神经切除猫舌的血管舒张反应。这些血管舒张因六甲铵预处理而显著降低，并且在切断舌远侧神经（DLN）和舌神经主干后几乎完全消失，但切断CTN后并未消失。目前的数据表明，CTN中的副交感舒血管纤维不参与猫舌的体-自主神经反射性血管舒张，并且体-自主神经反射性血管舒张反应的主要部分是由与DLN的三叉神经部分一起走行的副交感纤维作为猫舌中的舒血管纤维介导的。这也意味着存在两组副交感舒血管纤维，即一组起源于CTN（面神经），另一组起源于DLN的三叉神经部分（可能通过舌咽神经）。
