Stewart R B, Marks R G, Padgett P D, Hale W E
Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville.
Clin Ther. 1994 Jan-Feb;16(1):118-24.
A survey on use of benzodiazepines was conducted among participants in the Florida Geriatric Research Program. In 1978-79, benzodiazepine use was reported by 14.4% of 1448 women and 9.7% of 855 men; in 1984-85, by 12.0% of 1429 women and 5.9% of 784 men; and in 1991-92, by 13.4% of 1124 women and 6.6% of 497 men. The changes were not significant. During this period the mean ages of the women increased from 74.6 to 78.1 years and the men from 75.0 to 80.2 years. Chlordiazepoxide, diazepam, and flurazepam accounted for 98.1% of all benzodiazepines used in 1978-79 and for 35.5% in 1991-92, when alprazolam, lorazepam, and temazepam accounted for 47.1% of benzodiazepines used.
对佛罗里达老年研究项目的参与者进行了一项关于苯二氮䓬类药物使用情况的调查。1978 - 1979年，1448名女性中有14.4%报告使用苯二氮䓬类药物，855名男性中有9.7%报告使用；1984 - 1985年，1429名女性中有12.0%报告使用，784名男性中有5.9%报告使用；1991 - 1992年，1124名女性中有13.4%报告使用，497名男性中有6.6%报告使用。这些变化不显著。在此期间，女性的平均年龄从74.6岁增加到78.1岁，男性从75.0岁增加到80.2岁。氯氮䓬、地西泮和氟西泮在1978 - 1979年使用的所有苯二氮䓬类药物中占98.1%，而在1991 - 1992年占35.5%，此时阿普唑仑、劳拉西泮和替马西泮占所使用苯二氮䓬类药物的47.1%。
