Bertolini F, Lazzari L, Corsini C, Lauri E, Gorini F, Sirchia G
Division of Hematology, Maggiore Hospital, Milano, Italy.
Int J Artif Organs. 1993 Dec;16 Suppl 5:111-2.
Umbilical cord blood has been recently used as a source of hematopoietic progenitor cells for transplantation of pediatric patients. This study was performed to evaluate the feasibility of a cord blood bank for unrelated transplant. When the umbilical cord was clamped within 20 seconds after delivery, it was possible to collect 86 +/- 25 ml of cord recipients with more than 2000 CFU-GM/kg; 53% of cord blood samples were found to contain enough CFU-GM for engraftment in 50-70 kg adult patients.
脐带血最近已被用作儿科患者移植的造血祖细胞来源。本研究旨在评估脐带血库用于非亲属移植的可行性。当在分娩后20秒内夹紧脐带时，有可能采集到86±25毫升脐带血，其细胞集落生成单位-粒细胞巨噬细胞（CFU-GM）超过2000个/千克；发现53%的脐带血样本含有足够的CFU-GM，可用于50-70千克成年患者的植入。
