Walczewska B, Trzewikowska M
Katedry Higieny Akademii Medycznej, Lodzi.
Rocz Panstw Zakl Hig. 1993;44(2-3):181-9.
100 male rats, aged 30 +/- 1 days were investigated by means of 28 days study. The influence of the supplementation of glutaminic acid, histidine and arginine to the diet on dietary intake, weight gain and chemical composition was determined. It was casein that was used as the source of protein. We investigated the application of 4 kinds of diet during each experiment and the composition of the diets was based on the Miller-Bend non-protein diet model. The casein control diet contained 20g of casein per 100 g of diet. The diet with the supplementation of glutaminic acid contained 15 g of casein and 5 g of glutaminic acid per 100 g of diet. The histidine diet contained 15 g casein and 5 g of histidine per 100 g of diet. The arginine diet contained 15 g of casein and 5 g arginine per 100 g of diet. The addition of glutaminic acid, histidine and arginine to the diet caused the substantial decrease of diet intake weight gain and its ingredients. The addition of histidine to the diet reduced the nitrogen/total water contain ratio. This resulted in the inhibition of the chemical maturation of rat tissue and simultaneously decreased the percentage contain of fat in rat body.
选用100只30±1日龄的雄性大鼠进行为期28天的研究。测定了在日粮中添加谷氨酸、组氨酸和精氨酸对采食量、体重增加及化学成分的影响。以酪蛋白作为蛋白质来源。在每个实验中研究了4种日粮的应用情况，日粮组成基于米勒 - 本德无蛋白日粮模型。酪蛋白对照日粮每100克日粮含20克酪蛋白。添加谷氨酸的日粮每100克日粮含15克酪蛋白和5克谷氨酸。组氨酸日粮每100克日粮含15克酪蛋白和5克组氨酸。精氨酸日粮每100克日粮含15克酪蛋白和5克精氨酸。在日粮中添加谷氨酸、组氨酸和精氨酸导致采食量、体重增加及其成分大幅下降。在日粮中添加组氨酸降低了氮/总含水量比率。这导致大鼠组织化学成熟受到抑制，同时大鼠体内脂肪含量百分比降低。
