精神分裂症药物评估。诊断与患者选择。
Assessment of drugs in schizophrenia. Diagnosis and patient selection.
作者信息
Forrest A D
出版信息
Br J Clin Pharmacol. 1976 Jun;3(3 Suppl 2):367-70. doi: 10.1111/j.1365-2125.1976.tb03726.x.
It would seem that some set of operational definitions are required for the spectrum of psychotic patients often embraced by the rubric schizophrenia. The problems of acute (first-admission) and chronic patients have been described. At the present time 'relapse re-admissions' would seem to constitute the best population for drug evaluations. The importance of factors such as age, sex, ethnics, geography and length of history has been emphasized. Finally the importance of carefully excluding patients who would be at risk from pre-existing disease or hypersensitivity has been emphasized.
对于通常被纳入精神分裂症范畴的一系列精神病患者，似乎需要一套操作定义。急性（首次入院）和慢性患者的问题已被描述。目前，“复发再入院患者”似乎构成了药物评估的最佳人群。年龄、性别、种族、地理位置和病史长短等因素的重要性已得到强调。最后，强调了仔细排除那些因既往疾病或超敏反应而有风险的患者的重要性。
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