一种用于组装粘性菌毛的新型分泌装置。
A novel secretion apparatus for the assembly of adhesive bacterial pili.
作者信息
Jacob-Dubuisson F, Kuehn M, Hultgren S J
机构信息
Dept of Molecular Microbiology, Washington University Medical School, Saint Louis, MO 63110-1093.
出版信息
Trends Microbiol. 1993 May;1(2):50-5. doi: 10.1016/0966-842x(93)90032-m.
PMID:7913856
Abstract
The biogenesis of most types of bacterial pili requires two specialized proteins: a chaperone that caps the pilus subunits in the periplasm, and an outer membrane usher that receives the subunits and serves as an assembly platform. This secretion and assembly machinery is proposed to be a novel export apparatus found widely in Gram-negative pathogens.
摘要
大多数类型的细菌菌毛的生物合成需要两种特殊的蛋白质
一种伴侣蛋白，它在周质中封闭菌毛亚基；另一种外膜引导蛋白，它接收亚基并作为组装平台。这种分泌和组装机制被认为是一种广泛存在于革兰氏阴性病原体中的新型输出装置。
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