Jacob-Dubuisson F, Kuehn M, Hultgren S J
Dept of Molecular Microbiology, Washington University Medical School, Saint Louis, MO 63110-1093.
Trends Microbiol. 1993 May;1(2):50-5. doi: 10.1016/0966-842x(93)90032-m.
The biogenesis of most types of bacterial pili requires two specialized proteins: a chaperone that caps the pilus subunits in the periplasm, and an outer membrane usher that receives the subunits and serves as an assembly platform. This secretion and assembly machinery is proposed to be a novel export apparatus found widely in Gram-negative pathogens.
一种伴侣蛋白，它在周质中封闭菌毛亚基；另一种外膜引导蛋白，它接收亚基并作为组装平台。这种分泌和组装机制被认为是一种广泛存在于革兰氏阴性病原体中的新型输出装置。
