Abramets I I, Andreev P V, Komissarov I V, Samoĭlovich I M, Titievskiĭ A V
Biull Eksp Biol Med. 1993 Jan;115(1):51-3.
The nootropic drugs--nootropil, aethimizol, diethylaminoethanol, and ambocarb diminished of amnesia of active avoidance habit evoked by maximal electroconvulsive shock in the rats. At the same time tested nootropic drugs potentiated the frog spinal motoneurons responses mediated by NMDA, but not non NMDA glutamate receptors activation. It was discussed the role of NMDA-potentiating nootropic drugs action in their anti-amnestic action.
益智药——脑复康、乙硫异烟胺、二乙氨基乙醇和安波卡减轻了大鼠因最大电惊厥休克诱发的主动回避习惯失忆症。同时,所测试的益智药增强了由NMDA介导的青蛙脊髓运动神经元反应,但不增强非NMDA谷氨酸受体激活介导的反应。讨论了NMDA增强型益智药作用在其抗失忆作用中的作用。