自助餐式饮食对大鼠α-微球蛋白肠道吸收的影响。

Effect of cafeteria diet on alpha-MG intestinal absorption in rats.

作者信息

Dameto M C, Rayó J M, Esteban S, Prieto R M, Tur J A

机构信息

Department of Fund. Biology and Health Science, University of Balearic Islands, Palma de Mallorca, Spain.

出版信息

Comp Biochem Physiol Comp Physiol. 1994 Jun-Jul;108(2-3):467-70. doi: 10.1016/0300-9629(94)90120-1.

DOI:10.1016/0300-9629(94)90120-1

PMID:7914865

Abstract

The effect of a cafeteria diet (a hypercaloric diet) on the accumulative ability of the mediated and non-mediated small intestine transport of alpha-methyl-D-glucoside (alpha-MG) in developing female Wistar rats was studied using everted intestinal slices. Cafeteria diet increased intestinal active transport and decreased intestinal passive diffusion of alpha-MG in 30-day-old rats. No differences in alpha-MG intestinal absorption were found in cafeteria vs control rats after the development of obesity in cafeteria diet fed rats. A link between gastrointestinal functions and the development of obesity induced by cafeteria diet is suggested.

摘要

使用外翻肠段研究了自助餐饮食（高热量饮食）对发育中的雌性Wistar大鼠介导和非介导的α-甲基-D-葡萄糖苷（α-MG）小肠转运累积能力的影响。自助餐饮食增加了30日龄大鼠肠道对α-MG的主动转运并降低了其被动扩散。在喂食自助餐饮食的大鼠发生肥胖后，自助餐饮食组与对照组大鼠的α-MG肠道吸收没有差异。提示了胃肠功能与自助餐饮食诱导的肥胖发生之间的联系。