大鼠妊娠和哺乳期肠道α-甲基-D-葡萄糖苷摄取的变化
Changes in intestinal alpha-methyl-D-glucoside uptake due to pregnancy and lactation in rats.
作者信息
Prieto R M, Ferrer M, Tur J A
机构信息
Department of Fundamental Biology and Health Science, University of Balearic Islands, Palma de Mallorca, Spain.
出版信息
Digestion. 1996;57(1):16-21. doi: 10.1159/000201307.
Uptake of alpha-methyl-D-glucoside, a nonmetabolizable glucose analogue, by everted intestinal sleeves was studied in virgin, pregnant and lactating rats. The animals showed an increase in jejunal and ileal tissue mass, mucosal mass, nominal surface area, and enzymatic activities. No changes were observed in the carrier affinity throughout the breeding stages. Nevertheless there was a significant increase in glucose carrier density (Vmax) per unit of length of jejunum and ileum in pregnant and lactating animals. Integrating the results obtained, and increased overall ability to transport hexoses by nonspecific adaptation can be observed in breeding stages.
在未孕、怀孕和哺乳的大鼠中，研究了不可代谢的葡萄糖类似物α-甲基-D-葡萄糖苷被外翻肠套吸收的情况。这些动物的空肠和回肠组织质量、黏膜质量、标称表面积和酶活性均有所增加。在整个繁殖阶段，载体亲和力未观察到变化。然而，怀孕和哺乳动物的空肠和回肠单位长度的葡萄糖载体密度（Vmax）显著增加。综合所得结果，可以观察到在繁殖阶段通过非特异性适应，转运己糖的整体能力增强。
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